SARS-CoV-2: 두 판 사이의 차이

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'''2019년 신종 코로나바이러스'''({{llang|en|2019-nCoV}}), 공식적으로 '''SARS-CoV-2'''({{llang|en|severe acute respiratory syndrome coronavirus 2}}, 중증급성호흡기증후군 코로나바이러스 2형)<ref name=":1">{{저널 인용|last=Gorbalenya|first=Alexander E.|date=2020-02-11|title=Severe acute respiratory syndrome-related coronavirus – The species and its viruses, a statement of the Coronavirus Study Group|url=https://www.biorxiv.org/content/10.1101/2020.02.07.937862v1|journal=bioRxiv|language=en|pages=2020.02.07.937862|doi=10.1101/2020.02.07.937862}}</ref><ref name=":2">{{뉴스 인용|url=https://www.bbc.com/news/world-asia-china-51466362|title=Coronavirus disease named Covid-19|date=2020-02-11|work=BBC News|access-date=2020-02-11|language=en-GB}}</ref> 또는 '''2019년 신종 코로나바이러스'''({{llang|en|2019-nCoV}}), 비공식적으로 '''우한 코로나바이러스'''({{llang|en|Wuhan coronavirus}})<ref>{{웹 인용|url=https://www.npr.org/sections/goatsandsoda/2020/01/22/798277557/how-does-wuhan-coronavirus-compare-to-mers-sars-and-the-common-cold|title=How Does Wuhan Coronavirus Compare With MERS, SARS And The Common Cold?|last=Huang|first=Pien|date=January 22, 2020|website=NPR.org|language=en|url-status=live|access-date=2020-02-03|archive-url=https://web.archive.org/web/20200202094021/https://www.npr.org/sections/goatsandsoda/2020/01/22/798277557/how-does-wuhan-coronavirus-compare-to-mers-sars-and-the-common-cold|archive-date=2 February 2020}}</ref><ref name="Fox2020">{{저널 인용|last1=Fox|first1=Dan|title=What you need to know about the Wuhan coronavirus|journal=Nature|year=2020|issn=0028-0836|doi=10.1038/d41586-020-00209-y}}</ref>는 호흡기 감염을 일으키는 전염성 [[바이러스]]이다. [[2019코로나바이러스감염증-2020년 우한 코로나바이러스 유행|신종 코로나 바이러스19]] 발병 및 확산 과정에서의 원인균으로원인으로 알려졌다.<ref name=dph2020>{{웹 인용|url=http://www.dph.illinois.gov/topics-services/diseases-and-conditions/diseases-a-z-list/coronavirus/faq|제목=2019 Novel Coronavirus (2019 nCoV): Frequently Asked Questions {{!}} IDPH|website=www.dph.illinois.gov|access-date=27 January 2020}}</ref> 또한, 유전적 배열([[:en:Genomic sequencing|DNA sequencing]])에서 양방향(positive-sense) 외가닥 RNA(single-stranded RNA) 코로나19로 드러났다.<ref>{{웹 인용|url=http://www.chinacdc.cn/dfdt/201912/t20191226_209404.html|title=中国疾病预防控制中心|출판사=[[Chinese Center for Disease Control and Prevention]]|l출판위치=People's Republic of China|language=Chinese|accessdate=9 January 2020}}</ref><ref name=":xinhuanet9Jan2020">{{뉴스 인용|url=http://www.xinhuanet.com/english/2020-01/09/c_138690570.htm|제목=New-type coronavirus causes pneumonia in Wuhan: expert|l출판위치=People's Republic of China|accessdate=9 January 2020|agency=Xinhua|archive-url=https://web.archive.org/web/20200109084208/http://www.xinhuanet.com/english/2020-01/09/c_138690570.htm|archive-date=9 January 2020|url-status=live}}</ref><ref name=":gisaid">{{웹 인용|url=https://platform.gisaid.org/epi3/start/CoV2020|title=CoV2020|website=platform.gisaid.org|url-status=live|accessdate=12 January 2020|archive-url=https://web.archive.org/web/20200112130540/https://platform.gisaid.org/epi3/start/CoV2020|archive-date=12 January 2020}}</ref>
 
많은 초기 증례가 수산물 도매 시장과 연관되어, 이 바이러스가 동물에게서 유래된 것으로 생각되지만 이 사실이 정확하게 확인되지는 않았다.<ref name=CDC18Jan2020>[http://www.nj.gov/health/cd/documents/topics/NCOV/NCoV_LINCS_wuhan_update_011820_combined.pdf "Update and Interim Guidance on Outbreak of 2019 Novel Coronavirus (2019-nCoV) in Wuhan, China CDC Health Update"]. New Jersey Department of Health. 18 January 2020</ref> 유전적 배열과 그 외 바이러스 표본의 비교에서 [[중증급성호흡기증후군 코로나바이러스]]와 79.5%<ref name=":2">{{저널 인용|url=https://www.biorxiv.org/content/10.1101/2020.01.22.914952v2|제목=Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin|first1=Peng|last1=Zhou|first2=Xing-Lou|last2=Yang|first3=Xian-Guang|last3=Wang|first4=Ben|last4=Hu|first5=Lei|last5=Zhang|first6=Wei|last6=Zhang|first7=Hao-Rui|last7=Si|date=23 January 2020|journal=bioRxiv|pages=2020.01.22.914952|via=www.biorxiv.org|doi=10.1101/2020.01.22.914952}}</ref>, 박쥐 코로나바이러스와 96%<ref name=":2" /> 유사점이 있음이 드러났는데, 박쥐와 뱀에게 궁극적 기원이 있다는 것으로 추측이 되며,<ref name="Cyranoski">{{저널 인용|last=Callaway|first=Ewen|last2=Cyranoski|first2=David|date=23 January 2020|title=Why snakes probably aren't spreading the new China virus|url=https://www.nature.com/articles/d41586-020-00180-8|journal=Nature|doi=10.1038/d41586-020-00180-8|access-date=27 January 2020|archive-url=https://web.archive.org/web/20200125051951/https://www.nature.com/articles/d41586-020-00180-8|archive-date=25 January 2020|url-status=live}}</ref> [[천산갑]]과 같은 중간 숙주가 있는 것도 배제할 수 없다.<ref>{{웹 인용|url=https://www.dw.com/en/coronavirus-from-bats-to-pangolins-how-do-viruses-reach-us/a-52291570|title=Coronavirus: From bats to pangolins, how do viruses reach us?|website=DW|date=7 February 2020}}</ref><ref>{{웹 인용|url=http://virological.org/t/ncovs-relationship-to-bat-coronaviruses-recombination-signals-no-snakes-no-evidence-the-2019-ncov-lineage-is-recombinant/331|title=nCoV's relationship to bat coronaviruses & recombination signals (no snakes) - no evidence the 2019-nCoV lineage is recombinant|date=2020-01-22|website=Virological|language=en-US|access-date=2020-02-06|archive-url=https://web.archive.org/web/20200205101508/http://virological.org/t/ncovs-relationship-to-bat-coronaviruses-recombination-signals-no-snakes-no-evidence-the-2019-ncov-lineage-is-recombinant/331|archive-date=5 February 2020|url-status=live}}</ref>
 
== 병리학 ==
{{본문|2019코로나바이러스감염증-2020년 신종 코로나바이러스19|코로나바이러스감염증-19 유행}}
유증상 질환의 최초 사례가 3주 바로 전에 미리 2019년 12월 8일부터 발생하면서 최초 의심 증례가 WHO에 2019년 12월 31일 공지되었다.<ref>{{웹 인용|url=http://www.who.int/csr/don/12-january-2020-novel-coronavirus-china/en/|title=WHO {{!}} Novel Coronavirus – China|website=WHO|access-date=2020-02-01}}</ref> 분자 시계 접근법에서는 이와 유사하거나 그보다 앞선 유래 날짜를 제시한다.<ref name=early>{{저널 인용| last=Cohen | first=Jon | title=Wuhan seafood market may not be source of novel virus spreading globally | journal=Science | date=January 2020 | issn=0036-8075 | doi=10.1126/science.abb0611 | page=}}</ref> 2019년 신종 코로나바이러스 발병은 2019년 중순에 최초로 감지되었다. 출판된 유전체에 기초한 계통분류학에서는 해당 전파가 한 감염된 동물에게서 왔을 법하다는 것을 암시한다.<ref name=early>{{저널 인용| last=Cohen | first=Jon | title=Wuhan seafood market may not be source of novel virus spreading globally | journal=Science | date=January 2020 | issn=0036-8075 | doi=10.1126/science.abb0611 | page=}}</ref> 이 바이러스는 잇달아 중국의 다른 성 및 아시아, 유럽, 북미, 오세아니아의 20개 이상 국가에도 전파되었다.<ref name="GI2020Update">{{웹 인용|url=https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf6|title=Operations Dashboard for ArcGIS|last=|first=|date=2020-02-02|website=gisanddata.maps.arcgis.com|url-status=live|accessdate=2020-02-02}}</ref> 인간 대 인간 전염은 중국<ref>https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30154-9/fulltext</ref><ref name="auto">{{뉴스 인용|url=https://www.cbc.ca/news/health/coronavirus-human-to-human-1.5433187 |title=China confirms human-to-human transmission of new coronavirus |date=20 January 2020 |publisher=[[Canadian Broadcasting Corporation]] |accessdate=21 January 2020 |url-status=live |archive-url=https://web.archive.org/web/20200120173700/https://www.cbc.ca/news/health/coronavirus-human-to-human-1.5433187 |archive-date=20 January 2020 }}</ref>, 독일<ref>{{저널 인용|last1=Rothe |first1=Camilla|title=Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany |journal=NEJM |page=Correspondence to the Editor Page |doi=10.1056/NEJMc2001468 |pmid=32003551|year=2020}}</ref>, 태국<ref>{{웹 인용|url=https://www.bangkokpost.com/thailand/general/1847884/human-transmission-of-coronavirus-confirmed-in-thailand |title=Human transmission of coronavirus confirmed in Thailand |publisher=Bangkokpost.com |date= |accessdate=2020-02-01}}</ref>, 일본, 미국에서 확인되었다.<ref>{{웹 인용| title=The Coronavirus Is Now Infecting More People Outside China|url=https://www.wired.com/story/the-coronavirus-is-now-infecting-more-people-outside-china/|date=30 January 2020|work=[[Wired (magazine)|Wired]]|accessdate=30 January 2020}}</ref>