뷰티르산: 두 판 사이의 차이

뷰티레이트는 [[에너지 항상성]] 및 관련 질환([[당뇨병]] 및 [[비만증|비만]]), [[염증]] 및 [[면역계|면역]](예: 항균 및 [[항암 물질항발암물질|항암 효과]]가 있음)과 관련해서 사람에게 많은 유익한 효과를 제공한다.<ref name="Review - General summary as of April 2015, excluding neuroepigenetic research">{{저널 인용| vauthors = Kasubuchi M, Hasegawa S, Hiramatsu T, Ichimura A, Kimura I | title = Dietary gut microbial metabolites, short-chain fatty acids, and host metabolic regulation | journal = Nutrients | volume = 7 | issue = 4 | pages = 2839–49 | year = 2015 | pmid = 25875123 | pmc = 4425176 | doi = 10.3390/nu7042839 | quote = Short-chain fatty acids (SCFAs) such as acetate, butyrate, and propionate, which are produced by gut microbial fermentation of dietary fiber, are recognized as essential host energy sources and act as signal transduction molecules via G-protein coupled receptors (FFAR2, FFAR3, OLFR78, GPR109A) and as epigenetic regulators of gene expression by the inhibition of histone deacetylase (HDAC). Recent evidence suggests that dietary fiber and the gut microbial-derived SCFAs exert multiple beneficial effects on the host energy metabolism not only by improving the intestinal environment, but also by directly affecting various host peripheral tissues.}}</ref><ref name="Review for diabetes" /> 이러한 효과는 지방산 대사 동안 ATP를 생성하는 미토콘드리아에 의한 뷰티레이트의 이용을 통해 일어나거나 또는 하나 이상의 뷰티레이트의 [[히스톤 변형 효소]] 표적(즉, I형 히스톤 탈아세틸화효소) 및 [[G 단백질 연결 수용체|G-단백질 연결 수용체]](즉, FFAR2, FFAR3, and NIACR1)를 통해 일어난다.<ref name="Review - General summary as of April 2015, excluding neuroepigenetic research" />