감마-오리자놀

γ-Oryzanol
이름
	별칭 gamma-Oryzanol; gamma-Orizanol
식별자
CAS 번호	11042-64-1 ; Oryzanol A: 21238-33-5 ; Oryzanol C: 469-36-3 ; Campesteryl ferulate: 20972-07-0 ;
3D 모델 (JSmol)	Oryzanol A: Interactive image; Oryzanol C: Interactive image; Campesteryl ferulate: Interactive image;
ChemSpider	Oryzanol A: 4445360; Oryzanol C: 8095807; Campesteryl ferulate: 34987811;
ECHA InfoCard	100.110.371
PubChem CID	Oryzanol A: 12313778; Oryzanol C: 12313783; Campesteryl ferulate: 15056832;
UNII	SST9XCL51M ; Oryzanol A: 3PQR2YON9T ; Oryzanol C: HF5P8298M3 ; Campesteryl ferulate: 8BZA1H952Q ;
CompTox Dashboard (EPA)	DTXSID6021084 ;
	InChI Oryzanol A: InChI=1S/C40H58O4/c1-26(2)10-9-11-27(3)29-18-20-38(7)33-16-15-32-36(4,5)34(19-21-39(32)25-40(33,39)23-22-37(29,38)6)44-35(42)17-13-28-12-14-30(41)31(24-28)43-8/h10,12-14,17,24,27,29,32-34,41H,9,11,15-16,18-23,25H2,1-8H3/b17-13+ Key: FODTZLFLDFKIQH-GHRIWEEISA-N; Oryzanol C: InChI=1S/C41H60O4/c1-26(2)27(3)10-11-28(4)30-18-20-39(8)34-16-15-33-37(5,6)35(19-21-40(33)25-41(34,40)23-22-38(30,39)7)45-36(43)17-13-29-12-14-31(42)32(24-29)44-9/h12-14,17,24,26,28,30,33-35,42H,3,10-11,15-16,18-23,25H2,1-2,4-9H3/b17-13+ Key: JBSUVXVGZSMGDJ-GHRIWEEISA-N; Campesteryl ferulate: InChI=1S/C38H56O4/c1-24(2)25(3)8-9-26(4)31-14-15-32-30-13-12-28-23-29(18-20-37(28,5)33(30)19-21-38(31,32)6)42-36(40)17-11-27-10-16-34(39)35(22-27)41-7/h10-12,16-17,22,24-26,29-33,39H,8-9,13-15,18-21,23H2,1-7H3/b17-11+/t25-,26-,29+,30+,31-,32+,33+,37+,38-/m1/s1 Key: SWIWTAJTJOYCTB-NMYXBGBTSA-N;
	SMILES Oryzanol A: CC(CCC=C(C)C)C1CCC2(C1(CCC34C2CCC5C3(C4)CCC(C5(C)C)OC(=O)/C=C/C6=CC(=C(C=C6)O)OC)C)C; Oryzanol C: CC(C)C(=C)CCC(C)C1CCC2(C1(CCC34C2CCC5C3(C4)CCC(C5(C)C)OC(=O)/C=C/C6=CC(=C(C=C6)O)OC)C)C; Campesteryl ferulate: C[C@H](CC[C@@H](C)C(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)OC(=O)/C=C/C5=CC(=C(C=C5)O)OC)C)C;
성질
화학식	Mixture
겉보기	White to off-white solid
	달리 명시된 경우를 제외하면, 표준상태(25 °C [77 °F], 100 kPa)에서 물질의 정보가 제공됨. 정보상자 각주

감마오리자놀(gamma oryzanol,γ-Oryzanol) 또는 감마(γ)-오리자놀(Oryzanol)은 갱년기 장애와 자율 신경 기능 이상을 치료하는 약의 주요성분으로 알려져있다. 미배아유, 쌀겨기름에서 추출한 페르라산인 트리테르펜 알코올 에스테르가 시상 하부를 자극하고 자율 신경계와 내분비계의 실조를 개선한다.

감마오리자놀 편집

감마오리자놀(γ-Oryzanol)은 쌀(Oryza sativa)에서 추출한 지질의 혼합물이다.^[1] 감마오리자놀(γ-Oryzanol)은 쌀겨와 쌀겨 기름의 지방 분획에서 주로 발생하는 유기화합물이다.

원래는 단일 화합물로 생각되었지만^[2] 현재는 피토스테롤(phytosterols)와 트리테르페노이드(triterpenoids)의 페룰산(ferulic acid) 에스테르(esters)이다. 특히 시클로아르테닐 페놀산(cycloartenyl ferulate), 24-메틸렌시클로아르타닐 페놀산(24-methylenecycloartanyl ferulate), 캄페스테릴 페룰레이트(campesteryl ferulate)의 혼합물로 알려져 있으며,^[3] 이들 화합물은 감마(γ)-오리자놀의 80%를 차지한다.^[4]

같이 보기 편집

참고 편집

↑ R. M. Saunders (1985). “Rice bran: Composition and potential food uses”. 《Food Reviews International》 1 (3): 465–495. doi:10.1080/87559128509540780.
↑ Kaimal, T. B. N. (1999). “γ-Oryzanol from ricebran oil”. 《J Oil Technol Assoc India》 31: 83–93.
↑ Zhimin Xu and J. Samuel Godber (1999). “Purification and Identification of Components of γ-Oryzanol in Rice Bran Oil”. 《J. Agric. Food Chem.》 47 (7): 2724–2728. doi:10.1021/jf981175j. PMID 10552553.
↑ Xu Zhimin, Godber J S & Xu Z. “Antioxidant activities of major components of gamma-oryzanol from rice bran using a linolenic acid model”. 《J Am Oil Chem Soc》 78 (2001): 465–469.

[1] R. M. Saunders (1985). “Rice bran: Composition and potential food uses”. 《Food Reviews International》 1 (3): 465–495. doi:10.1080/87559128509540780.

[2] Kaimal, T. B. N. (1999). “γ-Oryzanol from ricebran oil”. 《J Oil Technol Assoc India》 31: 83–93.

[Godber-3] Zhimin Xu and J. Samuel Godber (1999). “Purification and Identification of Components of γ-Oryzanol in Rice Bran Oil”. 《J. Agric. Food Chem.》 47 (7): 2724–2728. doi:10.1021/jf981175j. PMID 10552553.

[4] Xu Zhimin, Godber J S & Xu Z. “Antioxidant activities of major components of gamma-oryzanol from rice bran using a linolenic acid model”. 《J Am Oil Chem Soc》 78 (2001): 465–469.

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이름
별칭 gamma-Oryzanol; gamma-Orizanol
식별자
CAS 번호	11042-64-1^예 Oryzanol A: 21238-33-5^예 Oryzanol C: 469-36-3^예 Campesteryl ferulate: 20972-07-0^예
3D 모델 (JSmol)	Oryzanol A: Interactive image Oryzanol C: Interactive image Campesteryl ferulate: Interactive image
ChemSpider	Oryzanol A: 4445360 Oryzanol C: 8095807 Campesteryl ferulate: 34987811
ECHA InfoCard	100.110.371
PubChem CID	Oryzanol A: 12313778 Oryzanol C: 12313783 Campesteryl ferulate: 15056832
UNII	SST9XCL51M^예 Oryzanol A: 3PQR2YON9T^예 Oryzanol C: HF5P8298M3^예 Campesteryl ferulate: 8BZA1H952Q^예
CompTox Dashboard (EPA)	DTXSID6021084
InChI Oryzanol A: InChI=1S/C40H58O4/c1-26(2)10-9-11-27(3)29-18-20-38(7)33-16-15-32-36(4,5)34(19-21-39(32)25-40(33,39)23-22-37(29,38)6)44-35(42)17-13-28-12-14-30(41)31(24-28)43-8/h10,12-14,17,24,27,29,32-34,41H,9,11,15-16,18-23,25H2,1-8H3/b17-13+ Key: FODTZLFLDFKIQH-GHRIWEEISA-N Oryzanol C: InChI=1S/C41H60O4/c1-26(2)27(3)10-11-28(4)30-18-20-39(8)34-16-15-33-37(5,6)35(19-21-40(33)25-41(34,40)23-22-38(30,39)7)45-36(43)17-13-29-12-14-31(42)32(24-29)44-9/h12-14,17,24,26,28,30,33-35,42H,3,10-11,15-16,18-23,25H2,1-2,4-9H3/b17-13+ Key: JBSUVXVGZSMGDJ-GHRIWEEISA-N Campesteryl ferulate: InChI=1S/C38H56O4/c1-24(2)25(3)8-9-26(4)31-14-15-32-30-13-12-28-23-29(18-20-37(28,5)33(30)19-21-38(31,32)6)42-36(40)17-11-27-10-16-34(39)35(22-27)41-7/h10-12,16-17,22,24-26,29-33,39H,8-9,13-15,18-21,23H2,1-7H3/b17-11+/t25-,26-,29+,30+,31-,32+,33+,37+,38-/m1/s1 Key: SWIWTAJTJOYCTB-NMYXBGBTSA-N
SMILES Oryzanol A: CC(CCC=C(C)C)C1CCC2(C1(CCC34C2CCC5C3(C4)CCC(C5(C)C)OC(=O)/C=C/C6=CC(=C(C=C6)O)OC)C)C Oryzanol C: CC(C)C(=C)CCC(C)C1CCC2(C1(CCC34C2CCC5C3(C4)CCC(C5(C)C)OC(=O)/C=C/C6=CC(=C(C=C6)O)OC)C)C Campesteryl ferulate: C[C@H](CC[C@@H](C)C(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)OC(=O)/C=C/C5=CC(=C(C=C5)O)OC)C)C
성질
화학식	Mixture
겉보기	White to off-white solid
달리 명시된 경우를 제외하면, 표준상태(25 °C [77 °F], 100 kPa)에서 물질의 정보가 제공됨. 정보상자 각주