안트라닐산: 두 판 사이의 차이
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잔글 봇: 화합물 정보 틀 이관 (chembox 또는 drugbox) |
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{{Chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 443392717
| ImageFileL1 = Anthranilsäure.svg
| ImageSizeL1 = 125
| ImageAltL1 = Skeletal formula of anthranilic acid
| ImageFileR1 = 2-Aminobenzoic-acid-3D-balls.png
| ImageSizeR1 = 125
| ImageNameR1 = C=black, H=white, O=red, N=blue
| ImageAltR1 = Ball-and-stick model of the anthranilic acid molecule
| PIN = 2-Aminobenzoic acid<ref name=iupac2013>{{cite book | title = Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book) | publisher = [[Royal Society of Chemistry|The Royal Society of Chemistry]] | date = 2014 | location = Cambridge | page = 748 | doi = 10.1039/9781849733069-FP001 | isbn = 978-0-85404-182-4| chapter = Front Matter }}</ref>
| SystematicName = 2-Aminobenzenecarboxylic acid
| OtherNames = {{Unbulleted list
| Anthranilic acid
| ''o''-Aminobenzoic acid
| 2-Aminobenzoic acid
| Vitamin L<sub>1</sub>
| Anthranilate (conjugate base)
|2-AA, 2AA, AA
}}
|Section1={{Chembox Identifiers
| KEGG_Ref = {{keggcite|correct|kegg}}
|
| InChI = 1/C7H7NO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,8H2,(H,9,10)
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 30754
| DrugBank_Ref = {{drugbankcite|changed|??}}
| DrugBank = DB04166
| SMILES = O=C(O)c1ccccc1N
| InChIKey = RWZYAGGXGHYGMB-UHFFFAOYAS
| SMILES1 = c1ccc(c(c1)C(=O)O)N
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 14173
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C7H7NO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,8H2,(H,9,10)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = RWZYAGGXGHYGMB-UHFFFAOYSA-N
| CASNo_Ref = {{cascite|correct|CAS}}
| CASNo = 118-92-3
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 222
| PubChem = 227
| EINECS = 204-287-5
| 3DMet = B00027
| Gmelin = 3397
| Beilstein = 471803
| UNII = 0YS975XI6W
<!-- | DrugBank = DB04056 (comment: can not have two drugbank values in Chembox)-->
| RTECS = CB2450000
}}
|Section2={{Chembox Properties
| C=7 | H=7 | N=1 | O=2
| Solubility = 0.572 g/100 mL (25 °C)
| SolubleOther = very soluble in [[chloroform]], [[pyridine]] <br> soluble in [[ethanol]], [[ether]], [[ethyl ether]] <br> slightly soluble in [[trifluoroacetic acid]], [[benzene]]
| Appearance = white or yellow solid
| Odor = odorless
| Density = 1.412 g/cm<sup>3</sup>
| MeltingPtC = 146 to 148
| MeltingPt_ref = <ref>[http://www.inchem.org/documents/icsc/icsc/eics1295.htm IPCS]</ref>
| BoilingPtC = 200
| BoilingPt_notes = (sublimes)
| pKa = {{Unbulleted list
| 2.17 (carboxyl; H<sub>2</sub>O)
| 4.85 (amino; H<sub>2</sub>O)<ref name="CRC97">{{cite book | editor= Haynes, William M. | year = 2016 | title = CRC Handbook of Chemistry and Physics | edition = 97th | publisher = [[CRC Press]] | isbn = 978-1498754286 | pages=5–89 | title-link = CRC Handbook of Chemistry and Physics }}</ref>
}}
| LogP = 1.21
| VaporPressure = 0.1 Pa (52.6 °C)
| RefractIndex = 1.578 (144 °C)
| MagSus = -77.18·10<sup>−6</sup> cm<sup>3</sup>/mol
}}
|Section4={{Chembox Thermochemistry
| DeltaHf = -380.4 KJ/mol
}}
|Section7={{Chembox Hazards
| ExternalSDS = [https://fscimage.fishersci.com/msds/83188.htm External MSDS]
| GHSPictograms = {{GHS05}}{{GHS07}}
| GHSSignalWord = Danger
| HPhrases = {{H-phrases|318|319}}
| PPhrases = {{P-phrases|264|280|305+351+338|310|337+313}}
| NFPA-H = 2
| NFPA-F = 1
| NFPA-R = 0
| AutoignitionPt = >
| AutoignitionPtC = 530
| FlashPt = >
| FlashPtC = 150
| LD50 = 1400 mg/kg (oral, rat)
}}
}}
'''안트라닐산'''({{llang|en|anthranilic acid}})은 [[화학식]]이 C<sub>6</sub>H<sub>4</sub>(NH<sub>2</sub>)(CO<sub>2</sub>H)인 [[방향족산]]이며 약간 달콤한 맛을 가지고 있다.<ref>{{서적 인용|url=https://books.google.com/books?id=sa2_I2GD2pUC|title=Aminobenzoic Acids—Advances in Research and Application|last=Acton|first=Q. Ashton|publisher=ScholarlyEditions|year=2013|isbn=9781481684842|edition=2013|location=Atlanta|pages=23|via=Google Books}}</ref><ref>{{서적 인용|url=https://books.google.com/books?id=mk-V2w6kHRgC|title=Techniques in Glycobiology|last=Hardy|first=Mark R.|publisher=Marcel Dekker, Inc.|year=1997|isbn=9780824798222|editor-last=Townsend|editor-first=R. Reid|location=|pages=360|chapter=Glycan Labeling with the Flurophores 2-Aminobenzamide and Antranilic Acid|editor-last2=Hotchkiss, Jr.|editor-first2=Arland T.|via=Google Books}}</ref><ref>''The Merck Index, 10th Ed.'' (1983), p.62., Rahway: Merck & Co.</ref> '''2-아미노벤조산'''({{llang|en|2-aminobenzoic acid}}) 또는 '''''o''-아미노벤조산'''({{llang|en|''o''-aminobenzoic acid}}), 줄여서 '''2-AA''', '''2AA''', '''AA'''라고 지칭하기도 한다. 안트라닐산은 [[카복실산]] 및 [[아민]]으로 오쏘 치환된 벤젠 고리로 구성된다. 산성 [[작용기]]와 염기성 작용기를 모두 가지고 있기 때문에 안트라닐산은 [[양쪽성]] 물질이다. 순수한 안트라닐산은 흰색 고체이지만 상업적 샘플은 노란색을 보일 수 있다. 안트라닐산의 탈양성자화에 의해 얻어진 음이온 [C<sub>6</sub>H<sub>4</sub>(NH<sub>2</sub>)(CO<sub>2</sub>)]<sup>−</sup>을 '''안트라닐레이트'''({{llang|en|anthranilate}})라고 한다. 안트라닐산은 과거에 비타민으로 여겨졌었고, 그러한 맥락에서 비타민 L<sub>1</sub>으로 불렸었지만, 현재는 사람의 영양에 필수적이지 않은 것으로 알려져 있다.<ref>{{웹 인용| author = Davidson, Michael W. | date = 2004 | url = http://micro.magnet.fsu.edu/vitamins/pages/anthranilic.html | title = Anthranilic Acid (Vitamin L)] | publisher = Florida State University | access-date = November 20, 2019 }}</ref>
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