후기 프로모팅 복합체 서브유닛 5 (Anaphase-promoting complex subunit 5)는 인간에서 ANAPC5 유전자에 의해 암호화되는 효소이다.[5][6]
후기 프로모팅 복합체 (Anaphase-promoting Complex, APC)는 APC5, CDC27, CDC16, CDC23을 포함하여 8개 이상의 단백질 서브유닛으로 구성된다.[6]
상호작용
편집
ANAPC5는 ANAPC1[7][8], ANAPC4, CDC27[9][10], PABPC1과 상호작용 하는 것으로 나타났다.
- ↑ 가 나 다 GRCh38: Ensembl release 89: ENSG00000089053 - 앙상블, May 2017
- ↑ 가 나 다 GRCm38: Ensembl release 89: ENSMUSG00000029472 - 앙상블, May 2017
- ↑ “Human PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》.
- ↑ “Mouse PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》.
- ↑ “Identification of a cullin homology region in a subunit of the anaphase-promoting complex”. 《Science》 279 (5354): 1219–22. March 1998. Bibcode:1998Sci...279.1219Y. doi:10.1126/science.279.5354.1219. PMID 9469815.
- ↑ 가 나 “Entrez Gene: ANAPC5 anaphase promoting complex subunit 5”.
- ↑ Vodermaier, Hartmut C; Gieffers, Christian; Maurer-Stroh, Sebastian; Eisenhaber, Frank; Peters, Jan-Michael (September 2003). “TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1”. 《Curr. Biol.》 13 (17): 1459–68. doi:10.1016/S0960-9822(03)00581-5. ISSN 0960-9822. PMID 12956947.
- ↑ Sumara, I; Vorlaufer E; Gieffers C; Peters B H; Peters J M (November 2000). “Characterization of Vertebrate Cohesin Complexes and Their Regulation in Prophase”. 《J. Cell Biol.》 151 (4): 749–62. doi:10.1083/jcb.151.4.749. ISSN 0021-9525. PMC 2169443. PMID 11076961.
- ↑ Koloteva-Levine, Nadejda; Pinchasi, Dalia; Pereman, Idan; Zur, Amit; Brandeis, Michael; Elroy-Stein, Orna (May 2004). “The Apc5 Subunit of the Anaphase-Promoting Complex/Cyclosome Interacts with Poly(A) Binding Protein and Represses Internal Ribosome Entry Site-Mediated Translation”. 《Mol. Cell. Biol.》 24 (9): 3577–87. doi:10.1128/MCB.24.9.3577-3587.2004. ISSN 0270-7306. PMC 387753. PMID 15082755.
- ↑ Gmachl, M; Gieffers C; Podtelejnikov A V; Mann M; Peters J M (August 2000). “The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex”. 《Proc. Natl. Acad. Sci. U.S.A.》 97 (16): 8973–8. Bibcode:2000PNAS...97.8973G. doi:10.1073/pnas.97.16.8973. ISSN 0027-8424. PMC 16806. PMID 10922056.