SFRS4

SRSF4
식별자
다른 이름	SRSF4, SFRS4, SRP75, serine/arginine-rich splicing factor 4, serine and arginine rich splicing factor 4
외부 ID	OMIM: 601940 MGI: 1890577 HomoloGene: 25624 GeneCards: SRSF4
유전자 위치 (인간)
염색체	1번 염색체
끝	29,181,900 bp
유전자 위치 (쥐)
염색체	4번 염색체 (쥐)
끝	131,901,706 bp
RNA 발현 패턴
	최상위 발현
	장딴지신경; ; middle frontal gyrus; ; 자궁목관; ; gastric mucosa; ; 오른허파; ; left lobe of thyroid gland; ; 왼자궁관; ; ganglionic eminence; ; right lobe of thyroid gland; ; upper lobe of left lung;
	최상위 발현
	상행대동맥; ; aortic valve; ; primitive streak; ; ganglionic eminence; ; somite; ; maxillary prominence; ; 망막색소상피세포; ; 수뇨관; ; 모낭; ; abdominal wall;
	추가 참조 발현 데이터
	추가 참조 발현 데이터
유전자 온톨로지
분자 함수	sequence-specific mRNA binding; nucleic acid binding; 단백질 결합; RNA binding; nucleotide binding;
세포 성분	세포핵; 핵질; nuclear speck;
생물학적 과정	RNA splicing, via transesterification reactions; mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; mRNA processing; negative regulation of mRNA splicing, via spliceosome; mRNA 3'-end processing; mRNA export from nucleus; RNA 스플라이싱; RNA export from nucleus; response to insulin; regulation of alternative mRNA splicing, via spliceosome; mRNA cis splicing, via spliceosome;
	출처: Amigo / QuickGO
동원체
	6429
	57317
	ENSG00000116350
	ENSMUSG00000028911
	Q08170
	Q8VE97
	NM_005626
	NM_020587
	NP_005617
	n/a
	위키데이터
인간 보기/편집	쥐 보기/편집

스플라이싱 인자, 아르기닌/세린 풍부 단백질 4(Splicing factor, arginine/serine-rich 4)는 인간에서 SFRS4 유전자에 의해 암호화되는 단백질이다.^[5]^[6]

상호작용 편집

SFRS4는 피닌과 상호작용하는 것으로 나타났다.^[7]

각주 편집

↑ ^가 ^나 ^다 GRCh38: Ensembl release 89: ENSG00000116350 - 앙상블, May 2017
↑ ^가 ^나 ^다 GRCm38: Ensembl release 89: ENSMUSG00000028911 - 앙상블, May 2017
↑ “Human PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》.
↑ “Mouse PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》.
↑ Zahler AM; Neugebauer KM; Stolk JA; Roth MB (Jul 1993). “Human SR proteins and isolation of a cDNA encoding SRp75”. 《Mol Cell Biol》 13 (7): 4023–8. doi:10.1128/MCB.13.7.4023. PMC 359951. PMID 8321209.
↑ “Entrez Gene: SFRS4 splicing factor, arginine/serine-rich 4”.
↑ Zimowska, Grazyna; Shi Jia; Munguba Gustavo; Jackson Moira R; Alpatov Roman; Simmons Matthew N; Shi Yujiang; Sugrue Stephen P (Nov 2003). “Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells”. 《Invest. Ophthalmol. Vis. Sci.》 44 (11): 4715–23. doi:10.1167/iovs.03-0240. ISSN 0146-0404. PMID 14578391.

[refGRCh38Ensembl-1] 가 ^나 ^다 GRCh38: Ensembl release 89: ENSG00000116350 - 앙상블, May 2017

[refGRCm38Ensembl-2] 가 ^나 ^다 GRCm38: Ensembl release 89: ENSMUSG00000028911 - 앙상블, May 2017

[3] “Human PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》.

[4] “Mouse PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》.

[pmid8321209-5] Zahler AM; Neugebauer KM; Stolk JA; Roth MB (Jul 1993). “Human SR proteins and isolation of a cDNA encoding SRp75”. 《Mol Cell Biol》 13 (7): 4023–8. doi:10.1128/MCB.13.7.4023. PMC 359951. PMID 8321209.

[entrez-6] “Entrez Gene: SFRS4 splicing factor, arginine/serine-rich 4”.

[pmid14578391-7] Zimowska, Grazyna; Shi Jia; Munguba Gustavo; Jackson Moira R; Alpatov Roman; Simmons Matthew N; Shi Yujiang; Sugrue Stephen P (Nov 2003). “Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells”. 《Invest. Ophthalmol. Vis. Sci.》 44 (11): 4715–23. doi:10.1167/iovs.03-0240. ISSN 0146-0404. PMID 14578391.

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